Commented Unassigned: Javascript Error using Editor in IE11 [27987]

I receive the JavaScript error "Error: Unable to get property 'parentNode' of undefined or null reference" in IE11 when I click on any of the toolbar buttons. This only happens when calling the set_content() method to set the text via JavaScript. The Editor toolbar buttons work fine if I don't use set_content() but unfortunately I have to. Changing the compatibility mode back to IE10 fixes the issue.
Comments: Please clarify the exact order of your actions. Am I right that you call set_content() first and then click any toolbar button?